| Santa Clarita to Smyrna (Delaware) | 2,372.57 mi (3,818.28 km) |
| Santa Clarita to Smyrna (Georgia) | 1,934.34 mi (3,113.03 km) |
| Santa Clarita to Smyrna (Tennessee) | 1,800.28 mi (2,897.27 km) |
| Santa Clarita to Snellville (Georgia) | 1,963.34 mi (3,159.69 km) |
| Santa Clarita to Snoqualmie (Washington) | 922.35 mi (1,484.38 km) |
| Santa Clarita to Snyder (Texas) | 1,017.92 mi (1,638.19 km) |
| Santa Clarita to Socastee (South Carolina) | 2,246.57 mi (3,615.50 km) |
| Santa Clarita to Socorro (Texas) | 733.84 mi (1,181.00 km) |
| Santa Clarita to Soddy-Daisy (Tennessee) | 1,881.70 mi (3,028.30 km) |
| Santa Clarita to Solana Beach (California) | 121.41 mi (195.39 km) |
| Santa Clarita to Soledad (California) | 212.74 mi (342.37 km) |
| Santa Clarita to Solon (Ohio) | 2,060.18 mi (3,315.53 km) |
| Santa Clarita to Somers Point (New Jersey) | 2,425.69 mi (3,903.77 km) |
| Santa Clarita to Somerset (Kentucky) | 1,898.95 mi (3,056.06 km) |
| Santa Clarita to Somerset (New Jersey) | 2,423.75 mi (3,900.65 km) |
