| Santa Clarita to Silver Firs (Washington) | 947.99 mi (1,525.64 km) |
| Santa Clarita to Silver Spring (Maryland) | 2,299.12 mi (3,700.07 km) |
| Santa Clarita to Silver Springs Shores (Florida) | 2,162.38 mi (3,480.01 km) |
| Santa Clarita to Silverdale (Washington) | 940.67 mi (1,513.86 km) |
| Santa Clarita to Silverton (Oregon) | 765.72 mi (1,232.30 km) |
| Santa Clarita to Simi Valley (California) | 17.80 mi (28.64 km) |
| Santa Clarita to Simpsonville (South Carolina) | 2,050.48 mi (3,299.92 km) |
| Santa Clarita to Sioux City (Iowa) | 1,314.67 mi (2,115.75 km) |
| Santa Clarita to Sioux Falls (South Dakota) | 1,322.43 mi (2,128.24 km) |
| Santa Clarita to Skokie (Illinois) | 1,739.58 mi (2,799.59 km) |
| Santa Clarita to Sleepy Hollow (New York) | 2,453.60 mi (3,948.69 km) |
| Santa Clarita to Slidell (Louisiana) | 1,694.22 mi (2,726.59 km) |
| Santa Clarita to Smithfield (North Carolina) | 2,258.62 mi (3,634.89 km) |
| Santa Clarita to Smithfield (Utah) | 627.29 mi (1,009.53 km) |
| Santa Clarita to Smithville (Missouri) | 1,361.15 mi (2,190.56 km) |
