| Santa Clarita to Santa Rosa (California) | 363.56 mi (585.10 km) |
| Santa Clarita to Santaquin (Utah) | 531.93 mi (856.07 km) |
| Santa Clarita to Santee (California) | 138.59 mi (223.03 km) |
| Santa Clarita to Sapulpa (Oklahoma) | 1,266.24 mi (2,037.82 km) |
| Santa Clarita to Saraland (Alabama) | 1,779.03 mi (2,863.07 km) |
| Santa Clarita to Sarasota (Florida) | 2,175.40 mi (3,500.98 km) |
| Santa Clarita to Sarasota Springs (Florida) | 2,180.09 mi (3,508.51 km) |
| Santa Clarita to Saratoga (California) | 279.04 mi (449.07 km) |
| Santa Clarita to Saratoga Springs (New York) | 2,452.26 mi (3,946.54 km) |
| Santa Clarita to Saratoga Springs (Utah) | 545.81 mi (878.39 km) |
| Santa Clarita to Sartell (Minnesota) | 1,490.74 mi (2,399.12 km) |
| Santa Clarita to Satellite Beach (Florida) | 2,264.94 mi (3,645.07 km) |
| Santa Clarita to Sauk Rapids (Minnesota) | 1,493.17 mi (2,403.03 km) |
| Santa Clarita to Sault Ste. Marie (Michigan) | 1,958.40 mi (3,151.74 km) |
| Santa Clarita to Savage (Minnesota) | 1,508.15 mi (2,427.13 km) |
