| Santa Clarita to San Clemente (California) | 83.97 mi (135.13 km) |
| Santa Clarita to San Diego (California) | 135.13 mi (217.48 km) |
| Santa Clarita to San Diego Country Estates (California) | 138.24 mi (222.48 km) |
| Santa Clarita to San Dimas (California) | 44.69 mi (71.93 km) |
| Santa Clarita to San Fernando (California) | 9.55 mi (15.36 km) |
| Santa Clarita to San Francisco (California) | 319.01 mi (513.39 km) |
| Santa Clarita to San Gabriel (California) | 31.81 mi (51.19 km) |
| Santa Clarita to San Germán (Puerto Rico) | 3,342.97 mi (5,379.99 km) |
| Santa Clarita to San Jacinto (California) | 96.17 mi (154.77 km) |
| Santa Clarita to San Jose (California) | 273.68 mi (440.44 km) |
| Santa Clarita to San Juan (Puerto Rico) | 3,387.88 mi (5,452.27 km) |
| Santa Clarita to San Juan (Texas) | 1,336.72 mi (2,151.25 km) |
| Santa Clarita to San Juan Capistrano (California) | 79.62 mi (128.14 km) |
| Santa Clarita to San Leandro (California) | 305.78 mi (492.11 km) |
| Santa Clarita to San Lorenzo (California) | 303.07 mi (487.74 km) |
