| Santa Clarita to Sacramento (California) | 330.83 mi (532.42 km) |
| Santa Clarita to Saddlebrooke (Arizona) | 457.51 mi (736.29 km) |
| Santa Clarita to Safety Harbor (Florida) | 2,149.76 mi (3,459.70 km) |
| Santa Clarita to Saginaw (Michigan) | 1,942.36 mi (3,125.93 km) |
| Santa Clarita to Saginaw (Texas) | 1,218.00 mi (1,960.17 km) |
| Santa Clarita to Sahuarita (Arizona) | 468.00 mi (753.17 km) |
| Santa Clarita to Saks (Alabama) | 1,860.90 mi (2,994.83 km) |
| Santa Clarita to Salem (Massachusetts) | 2,599.61 mi (4,183.66 km) |
| Santa Clarita to Salem (Ohio) | 2,090.52 mi (3,364.37 km) |
| Santa Clarita to Salem (Oregon) | 764.45 mi (1,230.26 km) |
| Santa Clarita to Salem (Virginia) | 2,147.13 mi (3,455.47 km) |
| Santa Clarita to Salem Lakes (Wisconsin) | 1,724.70 mi (2,775.64 km) |
| Santa Clarita to Salida (California) | 269.39 mi (433.55 km) |
| Santa Clarita to Salina (Kansas) | 1,194.30 mi (1,922.03 km) |
| Santa Clarita to Salinas (California) | 235.94 mi (379.70 km) |
