| Santa Clarita to Odenton (Maryland) | 2,316.18 mi (3,727.54 km) |
| Santa Clarita to Odessa (Texas) | 949.57 mi (1,528.18 km) |
| Santa Clarita to Ogden (Utah) | 589.83 mi (949.23 km) |
| Santa Clarita to Oildale (California) | 76.18 mi (122.60 km) |
| Santa Clarita to Ojus (Florida) | 2,348.09 mi (3,778.88 km) |
| Santa Clarita to Okemos (Michigan) | 1,913.61 mi (3,079.65 km) |
| Santa Clarita to Oklahoma City (Oklahoma) | 1,188.39 mi (1,912.54 km) |
| Santa Clarita to Okmulgee (Oklahoma) | 1,272.54 mi (2,047.95 km) |
| Santa Clarita to Olathe (Kansas) | 1,344.10 mi (2,163.12 km) |
| Santa Clarita to Old Jamestown (Missouri) | 1,587.24 mi (2,554.42 km) |
| Santa Clarita to Oldsmar (Florida) | 2,150.22 mi (3,460.45 km) |
| Santa Clarita to Olean (New York) | 2,215.95 mi (3,566.23 km) |
| Santa Clarita to Olive Branch (Mississippi) | 1,622.48 mi (2,611.12 km) |
| Santa Clarita to Olivehurst (California) | 363.89 mi (585.62 km) |
| Santa Clarita to Olney (Maryland) | 2,295.52 mi (3,694.28 km) |
