| Santa Clarita to Eugene (Oregon) | 710.10 mi (1,142.79 km) |
| Santa Clarita to Euless (Texas) | 1,234.46 mi (1,986.66 km) |
| Santa Clarita to Eureka (California) | 538.33 mi (866.37 km) |
| Santa Clarita to Eureka (Missouri) | 1,566.77 mi (2,521.47 km) |
| Santa Clarita to Eustis (Florida) | 2,187.52 mi (3,520.48 km) |
| Santa Clarita to Evans (Colorado) | 858.39 mi (1,381.45 km) |
| Santa Clarita to Evans (Georgia) | 2,072.64 mi (3,335.60 km) |
| Santa Clarita to Evanston (Illinois) | 1,742.00 mi (2,803.48 km) |
| Santa Clarita to Evanston (Wyoming) | 625.92 mi (1,007.32 km) |
| Santa Clarita to Evansville (Indiana) | 1,735.69 mi (2,793.32 km) |
| Santa Clarita to Everett (Massachusetts) | 2,592.35 mi (4,171.98 km) |
| Santa Clarita to Everett (Washington) | 954.16 mi (1,535.57 km) |
| Santa Clarita to Evergreen Park (Illinois) | 1,738.89 mi (2,798.47 km) |
| Santa Clarita to Ewa Beach (Hawaii) | 2,558.13 mi (4,116.92 km) |
| Santa Clarita to Ewa Gentry (Hawaii) | 2,558.64 mi (4,117.74 km) |
