| Santa Clarita to Eatontown (New Jersey) | 2,448.33 mi (3,940.20 km) |
| Santa Clarita to Eau Claire (Wisconsin) | 1,596.48 mi (2,569.29 km) |
| Santa Clarita to Echelon (New Jersey) | 2,401.50 mi (3,864.84 km) |
| Santa Clarita to Eden (North Carolina) | 2,171.14 mi (3,494.11 km) |
| Santa Clarita to Eden Prairie (Minnesota) | 1,505.90 mi (2,423.52 km) |
| Santa Clarita to Edgewater (Florida) | 2,227.12 mi (3,584.20 km) |
| Santa Clarita to Edgewater (New Jersey) | 2,449.64 mi (3,942.32 km) |
| Santa Clarita to Edgewood (Maryland) | 2,335.17 mi (3,758.09 km) |
| Santa Clarita to Edgewood (Washington) | 906.89 mi (1,459.50 km) |
| Santa Clarita to Edina (Minnesota) | 1,511.48 mi (2,432.49 km) |
| Santa Clarita to Edinburg (Texas) | 1,331.86 mi (2,143.42 km) |
| Santa Clarita to Edmond (Oklahoma) | 1,193.32 mi (1,920.46 km) |
| Santa Clarita to Edmonds (Washington) | 946.64 mi (1,523.47 km) |
| Santa Clarita to Edwards (Colorado) | 746.52 mi (1,201.41 km) |
| Santa Clarita to Edwardsville (Illinois) | 1,603.11 mi (2,579.96 km) |
