| Santa Clarita to Altus (Oklahoma) | 1,090.71 mi (1,755.33 km) |
| Santa Clarita to Alum Rock (California) | 276.16 mi (444.43 km) |
| Santa Clarita to Alvin (Texas) | 1,401.20 mi (2,255.02 km) |
| Santa Clarita to Amarillo (Texas) | 945.83 mi (1,522.17 km) |
| Santa Clarita to Amelia (Ohio) | 1,913.15 mi (3,078.92 km) |
| Santa Clarita to American Canyon (California) | 333.77 mi (537.15 km) |
| Santa Clarita to American Fork (Utah) | 551.84 mi (888.10 km) |
| Santa Clarita to Americus (Georgia) | 1,977.61 mi (3,182.66 km) |
| Santa Clarita to Ames (Iowa) | 1,442.47 mi (2,321.43 km) |
| Santa Clarita to Amherst (Ohio) | 2,019.26 mi (3,249.68 km) |
| Santa Clarita to Ammon (Idaho) | 717.13 mi (1,154.11 km) |
| Santa Clarita to Amsterdam (New York) | 2,431.58 mi (3,913.24 km) |
| Santa Clarita to Anacortes (Washington) | 995.05 mi (1,601.38 km) |
| Santa Clarita to Anaheim (California) | 54.16 mi (87.16 km) |
| Santa Clarita to Anchorage (Alaska) | 2,287.59 mi (3,681.53 km) |
