| Sanford to Oskaloosa (Iowa) | 1,074.75 mi (1,729.64 km) |
| Sanford to Oswego (Illinois) | 975.08 mi (1,569.24 km) |
| Sanford to Oswego (New York) | 1,047.06 mi (1,685.08 km) |
| Sanford to Otsego (Minnesota) | 1,323.01 mi (2,129.18 km) |
| Sanford to Ottawa (Illinois) | 966.57 mi (1,555.54 km) |
| Sanford to Ottawa (Kansas) | 1,049.46 mi (1,688.95 km) |
| Sanford to Ottumwa (Iowa) | 1,052.91 mi (1,694.49 km) |
| Sanford to Overland (Missouri) | 860.10 mi (1,384.19 km) |
| Sanford to Overland Park (Kansas) | 1,036.69 mi (1,668.39 km) |
| Sanford to Overlea (Maryland) | 779.43 mi (1,254.37 km) |
| Sanford to Oviedo (Florida) | 10.53 mi (16.94 km) |
| Sanford to Owasso (Oklahoma) | 991.88 mi (1,596.28 km) |
| Sanford to Owatonna (Minnesota) | 1,245.76 mi (2,004.86 km) |
| Sanford to Owensboro (Kentucky) | 705.18 mi (1,134.88 km) |
| Sanford to Owings Mills (Maryland) | 777.19 mi (1,250.77 km) |
