| San Mateo to Superior (Colorado) | 937.40 mi (1,508.59 km) |
| San Mateo to Superior (Wisconsin) | 1,660.13 mi (2,671.71 km) |
| San Mateo to Surprise (Arizona) | 614.59 mi (989.09 km) |
| San Mateo to Susanville (California) | 218.17 mi (351.11 km) |
| San Mateo to Sussex (Wisconsin) | 1,822.90 mi (2,933.68 km) |
| San Mateo to Suwanee (Georgia) | 2,141.94 mi (3,447.12 km) |
| San Mateo to Swansea (Illinois) | 1,751.08 mi (2,818.09 km) |
| San Mateo to Sweetwater (Florida) | 2,572.92 mi (4,140.72 km) |
| San Mateo to Sweetwater (Texas) | 1,284.91 mi (2,067.86 km) |
| San Mateo to Sycamore (Illinois) | 1,800.16 mi (2,897.08 km) |
| San Mateo to Sylacauga (Alabama) | 2,041.04 mi (3,284.74 km) |
| San Mateo to Sylvania (Ohio) | 2,056.76 mi (3,310.03 km) |
| San Mateo to Syosset (New York) | 2,589.97 mi (4,168.15 km) |
| San Mateo to Syracuse (New York) | 2,431.27 mi (3,912.75 km) |
| San Mateo to Syracuse (Utah) | 598.95 mi (963.91 km) |
