| San Marino to Southern Pines (North Carolina) | 2,187.23 mi (3,520.01 km) |
| San Marino to Southfield (Michigan) | 1,960.44 mi (3,155.02 km) |
| San Marino to Southgate (Michigan) | 1,961.54 mi (3,156.79 km) |
| San Marino to Southlake (Texas) | 1,207.84 mi (1,943.82 km) |
| San Marino to Spanaway (Washington) | 924.20 mi (1,487.36 km) |
| San Marino to Spanish Fork (Utah) | 545.87 mi (878.49 km) |
| San Marino to Spanish Lake (Missouri) | 1,577.46 mi (2,538.68 km) |
| San Marino to Spanish Springs (Nevada) | 391.92 mi (630.74 km) |
| San Marino to Sparks (Nevada) | 386.91 mi (622.67 km) |
| San Marino to Spartanburg (South Carolina) | 2,049.24 mi (3,297.93 km) |
| San Marino to Spearfish (South Dakota) | 1,044.74 mi (1,681.34 km) |
| San Marino to Speedway (Indiana) | 1,792.35 mi (2,884.51 km) |
| San Marino to Spencer (Iowa) | 1,380.94 mi (2,222.41 km) |
| San Marino to Spokane (Washington) | 936.51 mi (1,507.17 km) |
| San Marino to Spokane Valley (Washington) | 936.64 mi (1,507.38 km) |
