| San Giovanni Rotondo to Southern Pines (North Carolina) | 4,892.27 mi (7,873.35 km) |
| San Giovanni Rotondo to Southfield (Michigan) | 4,747.21 mi (7,639.89 km) |
| San Giovanni Rotondo to Southgate (Michigan) | 4,756.48 mi (7,654.81 km) |
| San Giovanni Rotondo to Southlake (Texas) | 5,749.20 mi (9,252.44 km) |
| San Giovanni Rotondo to Spanaway (Washington) | 5,787.45 mi (9,314.00 km) |
| San Giovanni Rotondo to Spanish Fork (Utah) | 5,893.59 mi (9,484.82 km) |
| San Giovanni Rotondo to Spanish Lake (Missouri) | 5,189.89 mi (8,352.33 km) |
| San Giovanni Rotondo to Spanish Springs (Nevada) | 6,158.09 mi (9,910.48 km) |
| San Giovanni Rotondo to Sparks (Nevada) | 6,164.29 mi (9,920.46 km) |
| San Giovanni Rotondo to Spartanburg (South Carolina) | 5,014.41 mi (8,069.91 km) |
| San Giovanni Rotondo to Spearfish (South Dakota) | 5,407.04 mi (8,701.80 km) |
| San Giovanni Rotondo to Speedway (Indiana) | 4,984.48 mi (8,021.74 km) |
| San Giovanni Rotondo to Spencer (Iowa) | 5,174.22 mi (8,327.10 km) |
| San Giovanni Rotondo to Spokane (Washington) | 5,631.21 mi (9,062.55 km) |
| San Giovanni Rotondo to Spokane Valley (Washington) | 5,626.37 mi (9,054.77 km) |
