| San Benedetto del Tronto to Southern Pines (North Carolina) | 4,767.35 mi (7,672.32 km) |
| San Benedetto del Tronto to Southfield (Michigan) | 4,619.58 mi (7,434.50 km) |
| San Benedetto del Tronto to Southgate (Michigan) | 4,628.90 mi (7,449.50 km) |
| San Benedetto del Tronto to Southlake (Texas) | 5,621.52 mi (9,046.97 km) |
| San Benedetto del Tronto to Spanaway (Washington) | 5,667.01 mi (9,120.16 km) |
| San Benedetto del Tronto to Spanish Fork (Utah) | 5,767.29 mi (9,281.56 km) |
| San Benedetto del Tronto to Spanish Lake (Missouri) | 5,062.17 mi (8,146.78 km) |
| San Benedetto del Tronto to Spanish Springs (Nevada) | 6,034.00 mi (9,710.79 km) |
| San Benedetto del Tronto to Sparks (Nevada) | 6,040.19 mi (9,720.75 km) |
| San Benedetto del Tronto to Spartanburg (South Carolina) | 4,888.95 mi (7,868.00 km) |
| San Benedetto del Tronto to Spearfish (South Dakota) | 5,280.16 mi (8,497.60 km) |
| San Benedetto del Tronto to Speedway (Indiana) | 4,856.99 mi (7,816.57 km) |
| San Benedetto del Tronto to Spencer (Iowa) | 5,046.28 mi (8,121.21 km) |
| San Benedetto del Tronto to Spokane (Washington) | 5,508.93 mi (8,865.76 km) |
| San Benedetto del Tronto to Spokane Valley (Washington) | 5,504.02 mi (8,857.86 km) |
