| Saint-Sebastien-sur-Loire to Southern Pines (North Carolina) | 3,963.59 mi (6,378.78 km) |
| Saint-Sebastien-sur-Loire to Southfield (Michigan) | 3,830.09 mi (6,163.93 km) |
| Saint-Sebastien-sur-Loire to Southgate (Michigan) | 3,838.67 mi (6,177.73 km) |
| Saint-Sebastien-sur-Loire to Southlake (Texas) | 4,832.10 mi (7,776.51 km) |
| Saint-Sebastien-sur-Loire to Spanaway (Washington) | 5,012.62 mi (8,067.03 km) |
| Saint-Sebastien-sur-Loire to Spanish Fork (Utah) | 5,037.53 mi (8,107.13 km) |
| Saint-Sebastien-sur-Loire to Spanish Lake (Missouri) | 4,273.98 mi (6,878.30 km) |
| Saint-Sebastien-sur-Loire to Spanish Springs (Nevada) | 5,334.49 mi (8,585.04 km) |
| Saint-Sebastien-sur-Loire to Sparks (Nevada) | 5,340.56 mi (8,594.80 km) |
| Saint-Sebastien-sur-Loire to Spartanburg (South Carolina) | 4,086.10 mi (6,575.94 km) |
| Saint-Sebastien-sur-Loire to Spearfish (South Dakota) | 4,542.06 mi (7,309.74 km) |
| Saint-Sebastien-sur-Loire to Speedway (Indiana) | 4,065.32 mi (6,542.50 km) |
| Saint-Sebastien-sur-Loire to Spencer (Iowa) | 4,280.20 mi (6,888.32 km) |
| Saint-Sebastien-sur-Loire to Spokane (Washington) | 4,834.86 mi (7,780.95 km) |
| Saint-Sebastien-sur-Loire to Spokane Valley (Washington) | 4,829.09 mi (7,771.66 km) |
