| Saco to Enterprise (Nevada) | 2,403.26 mi (3,867.67 km) |
| Saco to Enumclaw (Washington) | 2,468.17 mi (3,972.13 km) |
| Saco to Ephrata (Pennsylvania) | 374.59 mi (602.84 km) |
| Saco to Erie (Colorado) | 1,784.56 mi (2,871.97 km) |
| Saco to Erie (Pennsylvania) | 496.53 mi (799.08 km) |
| Saco to Erlanger (Kentucky) | 796.04 mi (1,281.09 km) |
| Saco to Escanaba (Michigan) | 829.94 mi (1,335.65 km) |
| Saco to Escondido (California) | 2,589.81 mi (4,167.90 km) |
| Saco to Española (New Mexico) | 1,944.89 mi (3,130.00 km) |
| Saco to Essex (Maryland) | 426.13 mi (685.79 km) |
| Saco to Essex Junction (Vermont) | 147.23 mi (236.95 km) |
| Saco to Estelle (Louisiana) | 1,435.26 mi (2,309.83 km) |
| Saco to Estero (Florida) | 1,342.14 mi (2,159.96 km) |
| Saco to Euclid (Ohio) | 578.04 mi (930.27 km) |
| Saco to Eufaula (Alabama) | 1,132.42 mi (1,822.46 km) |
