| Rye to Southern Pines (North Carolina) | 3,979.94 mi (6,405.09 km) |
| Rye to Southfield (Michigan) | 3,802.57 mi (6,119.64 km) |
| Rye to Southgate (Michigan) | 3,812.55 mi (6,135.70 km) |
| Rye to Southlake (Texas) | 4,802.99 mi (7,729.66 km) |
| Rye to Spanaway (Washington) | 4,868.88 mi (7,835.71 km) |
| Rye to Spanish Fork (Utah) | 4,941.66 mi (7,952.83 km) |
| Rye to Spanish Lake (Missouri) | 4,243.38 mi (6,829.05 km) |
| Rye to Spanish Springs (Nevada) | 5,217.36 mi (8,396.53 km) |
| Rye to Sparks (Nevada) | 5,223.51 mi (8,406.43 km) |
| Rye to Spartanburg (South Carolina) | 4,095.88 mi (6,591.68 km) |
| Rye to Spearfish (South Dakota) | 4,452.77 mi (7,166.04 km) |
| Rye to Speedway (Indiana) | 4,041.67 mi (6,504.44 km) |
| Rye to Spencer (Iowa) | 4,218.47 mi (6,788.97 km) |
| Rye to Spokane (Washington) | 4,701.58 mi (7,566.45 km) |
| Rye to Spokane Valley (Washington) | 4,696.29 mi (7,557.95 km) |
