| Runcorn to Southern Pines (North Carolina) | 3,794.08 mi (6,105.99 km) |
| Runcorn to Southfield (Michigan) | 3,600.19 mi (5,793.95 km) |
| Runcorn to Southgate (Michigan) | 3,610.63 mi (5,810.74 km) |
| Runcorn to Southlake (Texas) | 4,598.79 mi (7,401.04 km) |
| Runcorn to Spanaway (Washington) | 4,648.17 mi (7,480.50 km) |
| Runcorn to Spanish Fork (Utah) | 4,722.79 mi (7,600.60 km) |
| Runcorn to Spanish Lake (Missouri) | 4,039.39 mi (6,500.77 km) |
| Runcorn to Spanish Springs (Nevada) | 4,996.64 mi (8,041.32 km) |
| Runcorn to Sparks (Nevada) | 5,002.80 mi (8,051.23 km) |
| Runcorn to Spartanburg (South Carolina) | 3,906.96 mi (6,287.64 km) |
| Runcorn to Spearfish (South Dakota) | 4,234.97 mi (6,815.52 km) |
| Runcorn to Speedway (Indiana) | 3,840.22 mi (6,180.24 km) |
| Runcorn to Spencer (Iowa) | 4,006.02 mi (6,447.07 km) |
| Runcorn to Spokane (Washington) | 4,480.55 mi (7,210.75 km) |
| Runcorn to Spokane Valley (Washington) | 4,475.26 mi (7,202.24 km) |
