| Royal Leamington Spa to Southern Pines (North Carolina) | 3,860.52 mi (6,212.91 km) |
| Royal Leamington Spa to Southfield (Michigan) | 3,674.97 mi (5,914.29 km) |
| Royal Leamington Spa to Southgate (Michigan) | 3,685.17 mi (5,930.70 km) |
| Royal Leamington Spa to Southlake (Texas) | 4,674.62 mi (7,523.07 km) |
| Royal Leamington Spa to Spanaway (Washington) | 4,735.94 mi (7,621.76 km) |
| Royal Leamington Spa to Spanish Fork (Utah) | 4,807.46 mi (7,736.86 km) |
| Royal Leamington Spa to Spanish Lake (Missouri) | 4,115.06 mi (6,622.55 km) |
| Royal Leamington Spa to Spanish Springs (Nevada) | 5,083.10 mi (8,180.46 km) |
| Royal Leamington Spa to Sparks (Nevada) | 5,089.25 mi (8,190.36 km) |
| Royal Leamington Spa to Spartanburg (South Carolina) | 3,974.92 mi (6,397.02 km) |
| Royal Leamington Spa to Spearfish (South Dakota) | 4,318.83 mi (6,950.48 km) |
| Royal Leamington Spa to Speedway (Indiana) | 3,914.54 mi (6,299.84 km) |
| Royal Leamington Spa to Spencer (Iowa) | 4,086.43 mi (6,576.47 km) |
| Royal Leamington Spa to Spokane (Washington) | 4,567.89 mi (7,351.31 km) |
| Royal Leamington Spa to Spokane Valley (Washington) | 4,562.57 mi (7,342.75 km) |
