| Roseburg to Superior (Colorado) | 965.27 mi (1,553.44 km) |
| Roseburg to Superior (Wisconsin) | 1,537.12 mi (2,473.75 km) |
| Roseburg to Surprise (Arizona) | 883.04 mi (1,421.12 km) |
| Roseburg to Susanville (California) | 239.51 mi (385.46 km) |
| Roseburg to Sussex (Wisconsin) | 1,756.77 mi (2,827.24 km) |
| Roseburg to Suwanee (Georgia) | 2,190.49 mi (3,525.26 km) |
| Roseburg to Swansea (Illinois) | 1,760.41 mi (2,833.11 km) |
| Roseburg to Sweetwater (Florida) | 2,689.79 mi (4,328.80 km) |
| Roseburg to Sweetwater (Texas) | 1,448.48 mi (2,331.10 km) |
| Roseburg to Sycamore (Illinois) | 1,752.41 mi (2,820.23 km) |
| Roseburg to Sylacauga (Alabama) | 2,110.13 mi (3,395.92 km) |
| Roseburg to Sylvania (Ohio) | 2,004.24 mi (3,225.51 km) |
| Roseburg to Syosset (New York) | 2,526.11 mi (4,065.38 km) |
| Roseburg to Syracuse (New York) | 2,347.91 mi (3,778.60 km) |
| Roseburg to Syracuse (Utah) | 595.94 mi (959.07 km) |
