| Roseburg to Storm Lake (Iowa) | 1,418.14 mi (2,282.27 km) |
| Roseburg to Storrs (Connecticut) | 2,563.14 mi (4,124.97 km) |
| Roseburg to Stoughton (Wisconsin) | 1,710.60 mi (2,752.94 km) |
| Roseburg to Stow (Ohio) | 2,127.68 mi (3,424.17 km) |
| Roseburg to Streamwood (Illinois) | 1,777.01 mi (2,859.83 km) |
| Roseburg to Streator (Illinois) | 1,761.11 mi (2,834.23 km) |
| Roseburg to Streetsboro (Ohio) | 2,130.72 mi (3,429.07 km) |
| Roseburg to Strongsville (Ohio) | 2,105.17 mi (3,387.94 km) |
| Roseburg to Stuart (Florida) | 2,637.29 mi (4,244.31 km) |
| Roseburg to Stuarts Draft (Virginia) | 2,324.20 mi (3,740.43 km) |
| Roseburg to Sturgis (Michigan) | 1,917.92 mi (3,086.59 km) |
| Roseburg to Suamico (Wisconsin) | 1,744.72 mi (2,807.85 km) |
| Roseburg to Sudley (Virginia) | 2,380.41 mi (3,830.90 km) |
| Roseburg to Suffern (New York) | 2,487.61 mi (4,003.43 km) |
| Roseburg to Suffolk (Virginia) | 2,481.71 mi (3,993.92 km) |
