| Roseburg to Smyrna (Delaware) | 2,460.90 mi (3,960.43 km) |
| Roseburg to Smyrna (Georgia) | 2,174.21 mi (3,499.05 km) |
| Roseburg to Smyrna (Tennessee) | 2,006.18 mi (3,228.63 km) |
| Roseburg to Snellville (Georgia) | 2,200.22 mi (3,540.90 km) |
| Roseburg to Snoqualmie (Washington) | 306.41 mi (493.13 km) |
| Roseburg to Snyder (Texas) | 1,415.00 mi (2,277.22 km) |
| Roseburg to Socastee (South Carolina) | 2,457.16 mi (3,954.42 km) |
| Roseburg to Socorro (Texas) | 1,228.57 mi (1,977.20 km) |
| Roseburg to Soddy-Daisy (Tennessee) | 2,096.08 mi (3,373.32 km) |
| Roseburg to Solana Beach (California) | 780.00 mi (1,255.28 km) |
| Roseburg to Soledad (California) | 480.38 mi (773.10 km) |
| Roseburg to Solon (Ohio) | 2,122.95 mi (3,416.56 km) |
| Roseburg to Somers Point (New Jersey) | 2,509.85 mi (4,039.21 km) |
| Roseburg to Somerset (Kentucky) | 2,070.13 mi (3,331.55 km) |
| Roseburg to Somerset (New Jersey) | 2,484.72 mi (3,998.77 km) |
