| Roseburg to Silver Firs (Washington) | 325.84 mi (524.40 km) |
| Roseburg to Silver Spring (Maryland) | 2,398.41 mi (3,859.87 km) |
| Roseburg to Silver Springs Shores (Florida) | 2,472.61 mi (3,979.28 km) |
| Roseburg to Silverdale (Washington) | 308.70 mi (496.81 km) |
| Roseburg to Silverton (Oregon) | 126.20 mi (203.10 km) |
| Roseburg to Simi Valley (California) | 666.43 mi (1,072.52 km) |
| Roseburg to Simpsonville (South Carolina) | 2,259.60 mi (3,636.47 km) |
| Roseburg to Sioux City (Iowa) | 1,360.54 mi (2,189.58 km) |
| Roseburg to Sioux Falls (South Dakota) | 1,331.26 mi (2,142.46 km) |
| Roseburg to Skokie (Illinois) | 1,798.48 mi (2,894.38 km) |
| Roseburg to Sleepy Hollow (New York) | 2,501.29 mi (4,025.43 km) |
| Roseburg to Slidell (Louisiana) | 2,043.64 mi (3,288.93 km) |
| Roseburg to Smithfield (North Carolina) | 2,431.60 mi (3,913.29 km) |
| Roseburg to Smithfield (Utah) | 594.14 mi (956.17 km) |
| Roseburg to Smithville (Missouri) | 1,509.12 mi (2,428.70 km) |
