| Roseburg to Santa Rosa (California) | 331.80 mi (533.97 km) |
| Roseburg to Santaquin (Utah) | 637.41 mi (1,025.81 km) |
| Roseburg to Santee (California) | 795.11 mi (1,279.61 km) |
| Roseburg to Sapulpa (Oklahoma) | 1,525.62 mi (2,455.24 km) |
| Roseburg to Saraland (Alabama) | 2,104.10 mi (3,386.22 km) |
| Roseburg to Sarasota (Florida) | 2,517.93 mi (4,052.22 km) |
| Roseburg to Sarasota Springs (Florida) | 2,522.55 mi (4,059.65 km) |
| Roseburg to Saratoga (California) | 417.31 mi (671.60 km) |
| Roseburg to Saratoga Springs (New York) | 2,461.40 mi (3,961.24 km) |
| Roseburg to Saratoga Springs (Utah) | 621.26 mi (999.82 km) |
| Roseburg to Sartell (Minnesota) | 1,439.03 mi (2,315.90 km) |
| Roseburg to Satellite Beach (Florida) | 2,579.82 mi (4,151.82 km) |
| Roseburg to Sauk Rapids (Minnesota) | 1,442.35 mi (2,321.24 km) |
| Roseburg to Sault Ste. Marie (Michigan) | 1,902.95 mi (3,062.50 km) |
| Roseburg to Savage (Minnesota) | 1,486.06 mi (2,391.59 km) |
