| Roseburg to Sanford (Maine) | 2,598.22 mi (4,181.43 km) |
| Roseburg to Sanford (North Carolina) | 2,390.78 mi (3,847.59 km) |
| Roseburg to Sanger (California) | 493.39 mi (794.04 km) |
| Roseburg to Santa Ana (California) | 718.71 mi (1,156.65 km) |
| Roseburg to Santa Barbara (California) | 638.14 mi (1,026.99 km) |
| Roseburg to Santa Clara (California) | 411.28 mi (661.90 km) |
| Roseburg to Santa Clara (Oregon) | 62.60 mi (100.75 km) |
| Roseburg to Santa Clarita (California) | 661.87 mi (1,065.17 km) |
| Roseburg to Santa Cruz (California) | 437.00 mi (703.28 km) |
| Roseburg to Santa Fe (New Mexico) | 1,060.90 mi (1,707.35 km) |
| Roseburg to Santa Fe (Texas) | 1,827.21 mi (2,940.61 km) |
| Roseburg to Santa Fe Springs (California) | 702.22 mi (1,130.11 km) |
| Roseburg to Santa Maria (California) | 593.53 mi (955.20 km) |
| Roseburg to Santa Monica (California) | 687.54 mi (1,106.49 km) |
| Roseburg to Santa Paula (California) | 654.56 mi (1,053.41 km) |
