| Rocky Mount to Enterprise (Nevada) | 2,079.02 mi (3,345.86 km) |
| Rocky Mount to Enumclaw (Washington) | 2,375.70 mi (3,823.31 km) |
| Rocky Mount to Ephrata (Pennsylvania) | 304.13 mi (489.46 km) |
| Rocky Mount to Erie (Colorado) | 1,503.12 mi (2,419.03 km) |
| Rocky Mount to Erie (Pennsylvania) | 441.86 mi (711.11 km) |
| Rocky Mount to Erlanger (Kentucky) | 426.96 mi (687.13 km) |
| Rocky Mount to Escanaba (Michigan) | 830.63 mi (1,336.76 km) |
| Rocky Mount to Escondido (California) | 2,228.17 mi (3,585.90 km) |
| Rocky Mount to Española (New Mexico) | 1,574.58 mi (2,534.05 km) |
| Rocky Mount to Essex (Maryland) | 242.03 mi (389.51 km) |
| Rocky Mount to Essex Junction (Vermont) | 638.37 mi (1,027.35 km) |
| Rocky Mount to Estelle (Louisiana) | 828.41 mi (1,333.21 km) |
| Rocky Mount to Estero (Florida) | 699.95 mi (1,126.45 km) |
| Rocky Mount to Euclid (Ohio) | 436.82 mi (703.00 km) |
| Rocky Mount to Eufaula (Alabama) | 505.68 mi (813.81 km) |
