| Rock Island to Storm Lake (Iowa) | 250.12 mi (402.53 km) |
| Rock Island to Storrs (Connecticut) | 945.06 mi (1,520.92 km) |
| Rock Island to Stoughton (Wisconsin) | 122.21 mi (196.69 km) |
| Rock Island to Stow (Ohio) | 474.91 mi (764.29 km) |
| Rock Island to Streamwood (Illinois) | 129.68 mi (208.70 km) |
| Rock Island to Streator (Illinois) | 94.07 mi (151.40 km) |
| Rock Island to Streetsboro (Ohio) | 479.11 mi (771.05 km) |
| Rock Island to Strongsville (Ohio) | 453.56 mi (729.94 km) |
| Rock Island to Stuart (Florida) | 1,147.15 mi (1,846.16 km) |
| Rock Island to Stuarts Draft (Virginia) | 657.51 mi (1,058.17 km) |
| Rock Island to Sturgis (Michigan) | 267.61 mi (430.68 km) |
| Rock Island to Suamico (Wisconsin) | 252.86 mi (406.93 km) |
| Rock Island to Sudley (Virginia) | 714.96 mi (1,150.61 km) |
| Rock Island to Suffern (New York) | 852.56 mi (1,372.06 km) |
| Rock Island to Suffolk (Virginia) | 816.07 mi (1,313.33 km) |
