| Rock Island to Sanford (Maine) | 1,017.30 mi (1,637.18 km) |
| Rock Island to Sanford (North Carolina) | 741.59 mi (1,193.48 km) |
| Rock Island to Sanger (California) | 1,580.69 mi (2,543.88 km) |
| Rock Island to Santa Ana (California) | 1,578.99 mi (2,541.13 km) |
| Rock Island to Santa Barbara (California) | 1,651.41 mi (2,657.69 km) |
| Rock Island to Santa Clara (California) | 1,689.57 mi (2,719.10 km) |
| Rock Island to Santa Clara (Oregon) | 1,649.66 mi (2,654.87 km) |
| Rock Island to Santa Clarita (California) | 1,589.02 mi (2,557.29 km) |
| Rock Island to Santa Cruz (California) | 1,702.09 mi (2,739.24 km) |
| Rock Island to Santa Fe (New Mexico) | 921.83 mi (1,483.55 km) |
| Rock Island to Santa Fe (Texas) | 872.25 mi (1,403.75 km) |
| Rock Island to Santa Fe Springs (California) | 1,581.91 mi (2,545.84 km) |
| Rock Island to Santa Maria (California) | 1,673.73 mi (2,693.62 km) |
| Rock Island to Santa Monica (California) | 1,600.40 mi (2,575.60 km) |
| Rock Island to Santa Paula (California) | 1,620.08 mi (2,607.27 km) |
