| Rock Hill to Southern Pines (North Carolina) | 93.25 mi (150.08 km) |
| Rock Hill to Southfield (Michigan) | 534.34 mi (859.94 km) |
| Rock Hill to Southgate (Michigan) | 515.44 mi (829.51 km) |
| Rock Hill to Southlake (Texas) | 933.38 mi (1,502.12 km) |
| Rock Hill to Spanaway (Washington) | 2,283.97 mi (3,675.69 km) |
| Rock Hill to Spanish Fork (Utah) | 1,706.34 mi (2,746.09 km) |
| Rock Hill to Spanish Lake (Missouri) | 572.63 mi (921.55 km) |
| Rock Hill to Spanish Springs (Nevada) | 2,132.23 mi (3,431.50 km) |
| Rock Hill to Sparks (Nevada) | 2,135.08 mi (3,436.08 km) |
| Rock Hill to Spartanburg (South Carolina) | 51.03 mi (82.13 km) |
| Rock Hill to Spearfish (South Dakota) | 1,372.67 mi (2,209.09 km) |
| Rock Hill to Speedway (Indiana) | 441.05 mi (709.81 km) |
| Rock Hill to Spencer (Iowa) | 944.57 mi (1,520.13 km) |
| Rock Hill to Spokane (Washington) | 2,059.67 mi (3,314.72 km) |
| Rock Hill to Spokane Valley (Washington) | 2,050.58 mi (3,300.08 km) |
