| Roanoke Rapids to St. Simons (Georgia) | 422.38 mi (679.75 km) |
| Roanoke Rapids to Stafford (Texas) | 1,137.26 mi (1,830.25 km) |
| Roanoke Rapids to Stallings (North Carolina) | 192.36 mi (309.58 km) |
| Roanoke Rapids to Stamford (Connecticut) | 389.97 mi (627.59 km) |
| Roanoke Rapids to Stanford (California) | 2,436.34 mi (3,920.91 km) |
| Roanoke Rapids to Stanton (California) | 2,270.75 mi (3,654.42 km) |
| Roanoke Rapids to Star (Idaho) | 2,093.54 mi (3,369.23 km) |
| Roanoke Rapids to Starkville (Mississippi) | 665.42 mi (1,070.88 km) |
| Roanoke Rapids to State College (Pennsylvania) | 300.47 mi (483.56 km) |
| Roanoke Rapids to Staten Island (New York) | 342.77 mi (551.64 km) |
| Roanoke Rapids to Statesboro (Georgia) | 363.17 mi (584.46 km) |
| Roanoke Rapids to Statesville (North Carolina) | 185.55 mi (298.62 km) |
| Roanoke Rapids to Staunton (Virginia) | 141.59 mi (227.87 km) |
| Roanoke Rapids to Steamboat Springs (Colorado) | 1,595.31 mi (2,567.41 km) |
| Roanoke Rapids to Steiner Ranch (Texas) | 1,238.14 mi (1,992.59 km) |
