| Roanoke Rapids to St. George (Utah) | 1,977.15 mi (3,181.92 km) |
| Roanoke Rapids to St. Helens (Oregon) | 2,403.48 mi (3,868.03 km) |
| Roanoke Rapids to St. James (New York) | 390.50 mi (628.45 km) |
| Roanoke Rapids to St. John (Indiana) | 630.05 mi (1,013.96 km) |
| Roanoke Rapids to St. Joseph (Missouri) | 959.66 mi (1,544.43 km) |
| Roanoke Rapids to St. Louis (Missouri) | 705.87 mi (1,135.99 km) |
| Roanoke Rapids to St. Louis Park (Minnesota) | 1,008.54 mi (1,623.09 km) |
| Roanoke Rapids to St. Marys (Georgia) | 453.15 mi (729.28 km) |
| Roanoke Rapids to St. Marys (Pennsylvania) | 349.55 mi (562.55 km) |
| Roanoke Rapids to St. Matthews (Kentucky) | 456.03 mi (733.91 km) |
| Roanoke Rapids to St. Michael (Minnesota) | 1,031.12 mi (1,659.42 km) |
| Roanoke Rapids to St. Paul (Minnesota) | 997.50 mi (1,605.32 km) |
| Roanoke Rapids to St. Peter (Minnesota) | 1,014.07 mi (1,631.99 km) |
| Roanoke Rapids to St. Peters (Missouri) | 726.64 mi (1,169.41 km) |
| Roanoke Rapids to St. Petersburg (Florida) | 665.70 mi (1,071.34 km) |
