| Roanoke Rapids to Smyrna (Delaware) | 226.08 mi (363.84 km) |
| Roanoke Rapids to Smyrna (Georgia) | 426.87 mi (686.99 km) |
| Roanoke Rapids to Smyrna (Tennessee) | 495.84 mi (797.97 km) |
| Roanoke Rapids to Snellville (Georgia) | 400.98 mi (645.32 km) |
| Roanoke Rapids to Snoqualmie (Washington) | 2,359.08 mi (3,796.58 km) |
| Roanoke Rapids to Snyder (Texas) | 1,344.77 mi (2,164.20 km) |
| Roanoke Rapids to Socastee (South Carolina) | 205.49 mi (330.70 km) |
| Roanoke Rapids to Socorro (Texas) | 1,664.96 mi (2,679.49 km) |
| Roanoke Rapids to Soddy-Daisy (Tennessee) | 429.22 mi (690.76 km) |
| Roanoke Rapids to Solana Beach (California) | 2,246.27 mi (3,615.03 km) |
| Roanoke Rapids to Soledad (California) | 2,407.03 mi (3,873.73 km) |
| Roanoke Rapids to Solon (Ohio) | 397.51 mi (639.73 km) |
| Roanoke Rapids to Somers Point (New Jersey) | 258.60 mi (416.17 km) |
| Roanoke Rapids to Somerset (Kentucky) | 387.77 mi (624.06 km) |
| Roanoke Rapids to Somerset (New Jersey) | 328.28 mi (528.31 km) |
