| Roanoke Rapids to Shelton (Connecticut) | 414.18 mi (666.56 km) |
| Roanoke Rapids to Shelton (Washington) | 2,417.86 mi (3,891.16 km) |
| Roanoke Rapids to Shenandoah (Louisiana) | 874.76 mi (1,407.79 km) |
| Roanoke Rapids to Shepherdsville (Kentucky) | 455.42 mi (732.92 km) |
| Roanoke Rapids to Sheridan (Wyoming) | 1,631.27 mi (2,625.27 km) |
| Roanoke Rapids to Sherman (Texas) | 1,089.01 mi (1,752.60 km) |
| Roanoke Rapids to Sherrelwood (Colorado) | 1,498.73 mi (2,411.97 km) |
| Roanoke Rapids to Sherwood (Arkansas) | 823.73 mi (1,325.66 km) |
| Roanoke Rapids to Sherwood (Oregon) | 2,405.38 mi (3,871.09 km) |
| Roanoke Rapids to Shiloh (Illinois) | 687.46 mi (1,106.36 km) |
| Roanoke Rapids to Shiloh (Ohio) | 426.70 mi (686.71 km) |
| Roanoke Rapids to Shiloh (Pennsylvania) | 248.16 mi (399.37 km) |
| Roanoke Rapids to Shirley (New York) | 395.71 mi (636.83 km) |
| Roanoke Rapids to Shively (Kentucky) | 464.48 mi (747.50 km) |
| Roanoke Rapids to Shoreline (Washington) | 2,383.07 mi (3,835.19 km) |
