| Roanoke Rapids to San Luis Obispo (California) | 2,390.27 mi (3,846.77 km) |
| Roanoke Rapids to San Marcos (California) | 2,238.79 mi (3,602.98 km) |
| Roanoke Rapids to San Marcos (Texas) | 1,255.10 mi (2,019.89 km) |
| Roanoke Rapids to San Marino (California) | 2,271.17 mi (3,655.10 km) |
| Roanoke Rapids to San Mateo (California) | 2,442.23 mi (3,930.38 km) |
| Roanoke Rapids to San Pablo (California) | 2,438.00 mi (3,923.57 km) |
| Roanoke Rapids to San Rafael (California) | 2,447.18 mi (3,938.36 km) |
| Roanoke Rapids to San Ramon (California) | 2,419.11 mi (3,893.19 km) |
| Roanoke Rapids to San Tan Valley (Arizona) | 1,927.12 mi (3,101.39 km) |
| Roanoke Rapids to Sand Springs (Oklahoma) | 1,027.78 mi (1,654.05 km) |
| Roanoke Rapids to Sandusky (Ohio) | 439.33 mi (707.03 km) |
| Roanoke Rapids to Sandy (Oregon) | 2,377.52 mi (3,826.25 km) |
| Roanoke Rapids to Sandy (Utah) | 1,859.13 mi (2,991.98 km) |
| Roanoke Rapids to Sandy Springs (Georgia) | 417.09 mi (671.25 km) |
| Roanoke Rapids to Sanford (Florida) | 569.40 mi (916.37 km) |
