| Roanoke Rapids to San Diego (California) | 2,242.18 mi (3,608.45 km) |
| Roanoke Rapids to San Diego Country Estates (California) | 2,219.97 mi (3,572.69 km) |
| Roanoke Rapids to San Dimas (California) | 2,254.70 mi (3,628.59 km) |
| Roanoke Rapids to San Fernando (California) | 2,285.81 mi (3,678.65 km) |
| Roanoke Rapids to San Francisco (California) | 2,446.39 mi (3,937.08 km) |
| Roanoke Rapids to San Gabriel (California) | 2,270.91 mi (3,654.68 km) |
| Roanoke Rapids to San Germán (Puerto Rico) | 1,423.70 mi (2,291.23 km) |
| Roanoke Rapids to San Jacinto (California) | 2,215.58 mi (3,565.64 km) |
| Roanoke Rapids to San Jose (California) | 2,421.04 mi (3,896.28 km) |
| Roanoke Rapids to San Juan (Puerto Rico) | 1,432.45 mi (2,305.30 km) |
| Roanoke Rapids to San Juan (Texas) | 1,397.90 mi (2,249.70 km) |
| Roanoke Rapids to San Juan Capistrano (California) | 2,257.94 mi (3,633.80 km) |
| Roanoke Rapids to San Leandro (California) | 2,431.84 mi (3,913.67 km) |
| Roanoke Rapids to San Lorenzo (California) | 2,430.90 mi (3,912.16 km) |
| Roanoke Rapids to San Luis (Arizona) | 2,115.64 mi (3,404.79 km) |
