| Roanoke Rapids to Salisbury (New York) | 370.07 mi (595.57 km) |
| Roanoke Rapids to Salisbury (North Carolina) | 167.60 mi (269.73 km) |
| Roanoke Rapids to Salmon Creek (Washington) | 2,396.23 mi (3,856.36 km) |
| Roanoke Rapids to Salt Lake City (Utah) | 1,862.81 mi (2,997.90 km) |
| Roanoke Rapids to Sammamish (Washington) | 2,368.63 mi (3,811.94 km) |
| Roanoke Rapids to San Angelo (Texas) | 1,348.31 mi (2,169.89 km) |
| Roanoke Rapids to San Anselmo (California) | 2,449.85 mi (3,942.65 km) |
| Roanoke Rapids to San Antonio (Texas) | 1,299.42 mi (2,091.21 km) |
| Roanoke Rapids to San Benito (Texas) | 1,374.77 mi (2,212.49 km) |
| Roanoke Rapids to San Bernardino (California) | 2,225.74 mi (3,581.98 km) |
| Roanoke Rapids to San Bruno (California) | 2,447.54 mi (3,938.93 km) |
| Roanoke Rapids to San Buenaventura (California) | 2,329.76 mi (3,749.39 km) |
| Roanoke Rapids to San Carlos (California) | 2,440.64 mi (3,927.83 km) |
| Roanoke Rapids to San Carlos Park (Florida) | 731.08 mi (1,176.56 km) |
| Roanoke Rapids to San Clemente (California) | 2,256.51 mi (3,631.51 km) |
