| Roanoke Rapids to Saddlebrooke (Arizona) | 1,901.35 mi (3,059.92 km) |
| Roanoke Rapids to Safety Harbor (Florida) | 653.08 mi (1,051.02 km) |
| Roanoke Rapids to Saginaw (Michigan) | 585.84 mi (942.82 km) |
| Roanoke Rapids to Saginaw (Texas) | 1,145.36 mi (1,843.28 km) |
| Roanoke Rapids to Sahuarita (Arizona) | 1,919.79 mi (3,089.61 km) |
| Roanoke Rapids to Saks (Alabama) | 500.66 mi (805.74 km) |
| Roanoke Rapids to Salem (Massachusetts) | 552.08 mi (888.49 km) |
| Roanoke Rapids to Salem (Ohio) | 353.13 mi (568.30 km) |
| Roanoke Rapids to Salem (Oregon) | 2,415.17 mi (3,886.84 km) |
| Roanoke Rapids to Salem (Virginia) | 145.16 mi (233.62 km) |
| Roanoke Rapids to Salem Lakes (Wisconsin) | 698.75 mi (1,124.52 km) |
| Roanoke Rapids to Salida (California) | 2,374.25 mi (3,820.99 km) |
| Roanoke Rapids to Salina (Kansas) | 1,102.43 mi (1,774.19 km) |
| Roanoke Rapids to Salinas (California) | 2,418.75 mi (3,892.60 km) |
| Roanoke Rapids to Salisbury (Maryland) | 174.92 mi (281.51 km) |
