| Roanoke Rapids to Odenton (Maryland) | 188.45 mi (303.28 km) |
| Roanoke Rapids to Odessa (Texas) | 1,442.41 mi (2,321.34 km) |
| Roanoke Rapids to Ogden (Utah) | 1,863.90 mi (2,999.65 km) |
| Roanoke Rapids to Oildale (California) | 2,298.07 mi (3,698.38 km) |
| Roanoke Rapids to Ojus (Florida) | 739.67 mi (1,190.38 km) |
| Roanoke Rapids to Okemos (Michigan) | 562.52 mi (905.29 km) |
| Roanoke Rapids to Oklahoma City (Oklahoma) | 1,111.09 mi (1,788.12 km) |
| Roanoke Rapids to Okmulgee (Oklahoma) | 1,025.84 mi (1,650.92 km) |
| Roanoke Rapids to Olathe (Kansas) | 952.66 mi (1,533.15 km) |
| Roanoke Rapids to Old Jamestown (Missouri) | 710.18 mi (1,142.92 km) |
| Roanoke Rapids to Oldsmar (Florida) | 649.72 mi (1,045.63 km) |
| Roanoke Rapids to Olean (New York) | 391.70 mi (630.38 km) |
| Roanoke Rapids to Olive Branch (Mississippi) | 691.55 mi (1,112.94 km) |
| Roanoke Rapids to Olivehurst (California) | 2,381.92 mi (3,833.33 km) |
| Roanoke Rapids to Olney (Maryland) | 189.28 mi (304.62 km) |
