| Roanoke Rapids to Effingham (Illinois) | 622.89 mi (1,002.45 km) |
| Roanoke Rapids to Eggertsville (New York) | 454.75 mi (731.84 km) |
| Roanoke Rapids to Egypt Lake-Leto (Florida) | 647.54 mi (1,042.12 km) |
| Roanoke Rapids to El Cajon (California) | 2,233.85 mi (3,595.03 km) |
| Roanoke Rapids to El Campo (Texas) | 1,188.82 mi (1,913.22 km) |
| Roanoke Rapids to El Centro (California) | 2,156.60 mi (3,470.71 km) |
| Roanoke Rapids to El Cerrito (California) | 2,436.46 mi (3,921.10 km) |
| Roanoke Rapids to El Dorado (Arkansas) | 879.22 mi (1,414.97 km) |
| Roanoke Rapids to El Dorado (Kansas) | 1,060.66 mi (1,706.97 km) |
| Roanoke Rapids to El Dorado Hills (California) | 2,359.85 mi (3,797.80 km) |
| Roanoke Rapids to El Mirage (Arizona) | 1,961.62 mi (3,156.92 km) |
| Roanoke Rapids to El Monte (California) | 2,267.46 mi (3,649.13 km) |
| Roanoke Rapids to El Paso (Texas) | 1,669.65 mi (2,687.05 km) |
| Roanoke Rapids to El Paso de Robles (California) | 2,383.08 mi (3,835.20 km) |
| Roanoke Rapids to El Reno (Oklahoma) | 1,135.37 mi (1,827.20 km) |
