| Roanoke to The Villages (Florida) | 590.43 mi (950.21 km) |
| Roanoke to The Woodlands (Texas) | 1,017.88 mi (1,638.12 km) |
| Roanoke to Thibodaux (Louisiana) | 810.33 mi (1,304.10 km) |
| Roanoke to Thomasville (Georgia) | 500.75 mi (805.88 km) |
| Roanoke to Thomasville (North Carolina) | 96.78 mi (155.75 km) |
| Roanoke to Thonotosassa (Florida) | 652.08 mi (1,049.42 km) |
| Roanoke to Thornton (Colorado) | 1,356.96 mi (2,183.82 km) |
| Roanoke to Thousand Oaks (California) | 2,177.75 mi (3,504.74 km) |
| Roanoke to Three Lakes (Florida) | 804.46 mi (1,294.65 km) |
| Roanoke to Tiffin (Ohio) | 316.32 mi (509.06 km) |
| Roanoke to Tifton (Georgia) | 450.19 mi (724.50 km) |
| Roanoke to Tigard (Oregon) | 2,262.85 mi (3,641.70 km) |
| Roanoke to Tillmans Corner (Alabama) | 661.29 mi (1,064.24 km) |
| Roanoke to Timberlake (Virginia) | 39.11 mi (62.95 km) |
| Roanoke to Timberlane (Louisiana) | 772.18 mi (1,242.70 km) |
