| Roanoke to Sugar Hill (Georgia) | 317.52 mi (511.00 km) |
| Roanoke to Sugar Land (Texas) | 1,046.27 mi (1,683.81 km) |
| Roanoke to Sugarland Run (Virginia) | 185.29 mi (298.20 km) |
| Roanoke to Sugarmill Woods (Florida) | 608.68 mi (979.57 km) |
| Roanoke to Suisun City (California) | 2,277.86 mi (3,665.86 km) |
| Roanoke to Suitland (Maryland) | 197.58 mi (317.98 km) |
| Roanoke to Sulphur (Louisiana) | 909.46 mi (1,463.63 km) |
| Roanoke to Sulphur Springs (Texas) | 927.44 mi (1,492.57 km) |
| Roanoke to Summerfield (Maryland) | 202.11 mi (325.26 km) |
| Roanoke to Summerfield (North Carolina) | 74.77 mi (120.34 km) |
| Roanoke to Summerlin South (Nevada) | 1,949.78 mi (3,137.86 km) |
| Roanoke to Summerville (South Carolina) | 295.77 mi (476.00 km) |
| Roanoke to Summit (Illinois) | 521.50 mi (839.27 km) |
| Roanoke to Summit (New Jersey) | 382.75 mi (615.97 km) |
| Roanoke to Sumner (Washington) | 2,237.88 mi (3,601.52 km) |
