| Roanoke to St. George (Utah) | 1,840.83 mi (2,962.53 km) |
| Roanoke to St. Helens (Oregon) | 2,264.04 mi (3,643.61 km) |
| Roanoke to St. James (New York) | 441.43 mi (710.41 km) |
| Roanoke to St. John (Indiana) | 493.46 mi (794.15 km) |
| Roanoke to St. Joseph (Missouri) | 820.52 mi (1,320.50 km) |
| Roanoke to St. Louis (Missouri) | 567.89 mi (913.93 km) |
| Roanoke to St. Louis Park (Minnesota) | 874.40 mi (1,407.20 km) |
| Roanoke to St. Marys (Georgia) | 459.97 mi (740.25 km) |
| Roanoke to St. Marys (Pennsylvania) | 298.57 mi (480.50 km) |
| Roanoke to St. Matthews (Kentucky) | 317.38 mi (510.77 km) |
| Roanoke to St. Michael (Minnesota) | 897.26 mi (1,443.99 km) |
| Roanoke to St. Paul (Minnesota) | 863.65 mi (1,389.91 km) |
| Roanoke to St. Peter (Minnesota) | 877.90 mi (1,412.85 km) |
| Roanoke to St. Peters (Missouri) | 588.39 mi (946.92 km) |
| Roanoke to St. Petersburg (Florida) | 673.99 mi (1,084.68 km) |
