| Roanoke to South Fulton (Georgia) | 362.27 mi (583.02 km) |
| Roanoke to South Gate (California) | 2,145.43 mi (3,452.73 km) |
| Roanoke to South Hill (Washington) | 2,240.04 mi (3,605.00 km) |
| Roanoke to South Holland (Illinois) | 505.08 mi (812.84 km) |
| Roanoke to South Houston (Texas) | 1,023.51 mi (1,647.19 km) |
| Roanoke to South Huntington (New York) | 428.85 mi (690.17 km) |
| Roanoke to South Jordan (Utah) | 1,726.58 mi (2,778.65 km) |
| Roanoke to South Lake Tahoe (California) | 2,161.45 mi (3,478.52 km) |
| Roanoke to South Laurel (Maryland) | 209.12 mi (336.55 km) |
| Roanoke to South Lyon (Michigan) | 408.09 mi (656.75 km) |
| Roanoke to South Miami (Florida) | 799.70 mi (1,286.99 km) |
| Roanoke to South Miami Heights (Florida) | 808.09 mi (1,300.49 km) |
| Roanoke to South Milwaukee (Wisconsin) | 570.53 mi (918.18 km) |
| Roanoke to South Ogden (Utah) | 1,723.82 mi (2,774.22 km) |
| Roanoke to South Pasadena (California) | 2,140.12 mi (3,444.19 km) |
