| Roanoke to San Diego (California) | 2,110.68 mi (3,396.81 km) |
| Roanoke to San Diego Country Estates (California) | 2,088.33 mi (3,360.84 km) |
| Roanoke to San Dimas (California) | 2,121.11 mi (3,413.59 km) |
| Roanoke to San Fernando (California) | 2,151.78 mi (3,462.96 km) |
| Roanoke to San Francisco (California) | 2,308.18 mi (3,714.65 km) |
| Roanoke to San Gabriel (California) | 2,137.24 mi (3,439.56 km) |
| Roanoke to San Germán (Puerto Rico) | 1,540.11 mi (2,478.56 km) |
| Roanoke to San Jacinto (California) | 2,082.70 mi (3,351.79 km) |
| Roanoke to San Jose (California) | 2,283.23 mi (3,674.50 km) |
| Roanoke to San Juan (Puerto Rico) | 1,552.34 mi (2,498.25 km) |
| Roanoke to San Juan (Texas) | 1,311.35 mi (2,110.41 km) |
| Roanoke to San Juan Capistrano (California) | 2,125.24 mi (3,420.24 km) |
| Roanoke to San Leandro (California) | 2,293.70 mi (3,691.36 km) |
| Roanoke to San Lorenzo (California) | 2,292.79 mi (3,689.89 km) |
| Roanoke to San Luis (Arizona) | 1,985.80 mi (3,195.84 km) |
