| Roanoke to Montgomeryville (Pennsylvania) | 326.64 mi (525.68 km) |
| Roanoke to Monticello (Minnesota) | 905.31 mi (1,456.96 km) |
| Roanoke to Montrose (Colorado) | 1,518.12 mi (2,443.18 km) |
| Roanoke to Moody (Alabama) | 447.15 mi (719.62 km) |
| Roanoke to Moore (Oklahoma) | 983.21 mi (1,582.32 km) |
| Roanoke to Moorestown-Lenola (New Jersey) | 327.24 mi (526.65 km) |
| Roanoke to Mooresville (North Carolina) | 126.60 mi (203.74 km) |
| Roanoke to Moorhead (Minnesota) | 1,082.55 mi (1,742.20 km) |
| Roanoke to Moorpark (California) | 2,175.90 mi (3,501.78 km) |
| Roanoke to Moraga (California) | 2,289.68 mi (3,684.88 km) |
| Roanoke to Moreno Valley (California) | 2,091.75 mi (3,366.35 km) |
| Roanoke to Morgan City (Louisiana) | 831.31 mi (1,337.87 km) |
| Roanoke to Morgan Hill (California) | 2,274.83 mi (3,660.99 km) |
| Roanoke to Morganton (North Carolina) | 143.69 mi (231.24 km) |
| Roanoke to Morgantown (West Virginia) | 163.05 mi (262.40 km) |
