| Roanoke to Merriam (Kansas) | 808.70 mi (1,301.48 km) |
| Roanoke to Merrick (New York) | 415.39 mi (668.50 km) |
| Roanoke to Merrifield (Virginia) | 184.25 mi (296.52 km) |
| Roanoke to Merrillville (Indiana) | 488.13 mi (785.57 km) |
| Roanoke to Merritt Island (Florida) | 620.77 mi (999.03 km) |
| Roanoke to Mesa (Arizona) | 1,801.38 mi (2,899.04 km) |
| Roanoke to Mesquite (Nevada) | 1,874.69 mi (3,017.02 km) |
| Roanoke to Mesquite (Texas) | 989.74 mi (1,592.83 km) |
| Roanoke to Metairie (Louisiana) | 772.86 mi (1,243.80 km) |
| Roanoke to Methuen Town (Massachusetts) | 597.32 mi (961.29 km) |
| Roanoke to Metuchen (New Jersey) | 375.83 mi (604.84 km) |
| Roanoke to Mexico (Missouri) | 659.12 mi (1,060.75 km) |
| Roanoke to Miami (Florida) | 794.33 mi (1,278.35 km) |
| Roanoke to Miami (Oklahoma) | 821.60 mi (1,322.23 km) |
| Roanoke to Miami Beach (Florida) | 791.98 mi (1,274.56 km) |
