| Roanoke to Medford (Massachusetts) | 588.28 mi (946.74 km) |
| Roanoke to Medford (New York) | 446.88 mi (719.18 km) |
| Roanoke to Medford (Oregon) | 2,278.98 mi (3,667.67 km) |
| Roanoke to Medina (Ohio) | 285.46 mi (459.41 km) |
| Roanoke to Medulla (Florida) | 654.73 mi (1,053.69 km) |
| Roanoke to Mehlville (Missouri) | 570.71 mi (918.46 km) |
| Roanoke to Melbourne (Florida) | 634.90 mi (1,021.77 km) |
| Roanoke to Melissa (Texas) | 974.44 mi (1,568.20 km) |
| Roanoke to Melrose (Massachusetts) | 591.62 mi (952.13 km) |
| Roanoke to Melrose Park (Illinois) | 528.07 mi (849.85 km) |
| Roanoke to Melville (New York) | 426.62 mi (686.58 km) |
| Roanoke to Melvindale (Michigan) | 385.49 mi (620.39 km) |
| Roanoke to Memphis (Florida) | 689.45 mi (1,109.57 km) |
| Roanoke to Memphis (Tennessee) | 577.52 mi (929.43 km) |
| Roanoke to Menasha (Wisconsin) | 652.02 mi (1,049.33 km) |
