| Roanoke to McHenry (Illinois) | 563.40 mi (906.71 km) |
| Roanoke to McKeesport (Pennsylvania) | 211.74 mi (340.77 km) |
| Roanoke to McKinleyville (California) | 2,354.08 mi (3,788.52 km) |
| Roanoke to McKinney (Texas) | 982.53 mi (1,581.24 km) |
| Roanoke to McLean (Virginia) | 189.22 mi (304.52 km) |
| Roanoke to McMinnville (Oregon) | 2,282.96 mi (3,674.07 km) |
| Roanoke to McMinnville (Tennessee) | 341.61 mi (549.77 km) |
| Roanoke to McNair (Virginia) | 180.33 mi (290.21 km) |
| Roanoke to McPherson (Kansas) | 967.58 mi (1,557.17 km) |
| Roanoke to Mead Valley (California) | 2,098.04 mi (3,376.47 km) |
| Roanoke to Meadow Woods (Florida) | 620.77 mi (999.03 km) |
| Roanoke to Meadowbrook (Virginia) | 136.83 mi (220.21 km) |
| Roanoke to Meadville (Pennsylvania) | 302.04 mi (486.09 km) |
| Roanoke to Mebane (North Carolina) | 90.75 mi (146.05 km) |
| Roanoke to Mechanicsville (Virginia) | 144.72 mi (232.91 km) |
