| Roanoke to Lewiston (Idaho) | 1,986.97 mi (3,197.72 km) |
| Roanoke to Lewiston (Maine) | 695.29 mi (1,118.95 km) |
| Roanoke to Lewisville (North Carolina) | 85.10 mi (136.95 km) |
| Roanoke to Lewisville (Texas) | 1,003.42 mi (1,614.86 km) |
| Roanoke to Lexington (Kentucky) | 251.74 mi (405.13 km) |
| Roanoke to Lexington (Nebraska) | 1,086.74 mi (1,748.95 km) |
| Roanoke to Lexington (North Carolina) | 103.47 mi (166.52 km) |
| Roanoke to Lexington (South Carolina) | 238.07 mi (383.14 km) |
| Roanoke to Lexington Park (Maryland) | 203.47 mi (327.45 km) |
| Roanoke to Liberal (Kansas) | 1,152.47 mi (1,854.72 km) |
| Roanoke to Liberty (Missouri) | 795.27 mi (1,279.87 km) |
| Roanoke to Liberty Lake (Washington) | 2,001.55 mi (3,221.19 km) |
| Roanoke to Liberty Triangle (Florida) | 581.57 mi (935.94 km) |
| Roanoke to Libertyville (Illinois) | 547.82 mi (881.64 km) |
| Roanoke to Lighthouse Point (Florida) | 760.07 mi (1,223.21 km) |
