| Roanoke to Laredo (Texas) | 1,318.15 mi (2,121.36 km) |
| Roanoke to Largo (Florida) | 667.67 mi (1,074.52 km) |
| Roanoke to Largo (Maryland) | 202.98 mi (326.66 km) |
| Roanoke to Larkspur (California) | 2,310.05 mi (3,717.66 km) |
| Roanoke to Las Cruces (New Mexico) | 1,554.60 mi (2,501.89 km) |
| Roanoke to Las Vegas (Nevada) | 1,944.45 mi (3,129.28 km) |
| Roanoke to Las Vegas (New Mexico) | 1,404.79 mi (2,260.80 km) |
| Roanoke to Latham (New York) | 500.18 mi (804.97 km) |
| Roanoke to Lathrop (California) | 2,247.01 mi (3,616.21 km) |
| Roanoke to Lauderdale Lakes (Florida) | 767.78 mi (1,235.62 km) |
| Roanoke to Lauderhill (Florida) | 768.34 mi (1,236.52 km) |
| Roanoke to Laurel (Florida) | 714.72 mi (1,150.23 km) |
| Roanoke to Laurel (Maryland) | 209.78 mi (337.61 km) |
| Roanoke to Laurel (Mississippi) | 649.47 mi (1,045.22 km) |
| Roanoke to Laurel (Virginia) | 136.74 mi (220.06 km) |
